Sp Primobol

Buy Primobol is used in the treatment of protein synthesis disorders, cachexia of various formations; trauma, extensive burns after irradiation and infectious diseases; muscular dystrophy, osteoporosis, negative nitrogen balance, corticosteroid therapy, hypo- and aplastic anemia.

Contraindications:

This drug is contraindicated in patients with hypersensitivity to the drug, prostate cancer, breast cancer in men, breast cancer in women, hypercalcemia, CPI, severe atherosclerosis, nephrotic syndrome, acute and chronic liver disease, nephritis, pregnancy, lactation.

Management:

The drug is administered 1 ml deep intramuscularly every 2 weeks. Once the desired result is achieved, 1 ml can be applied every 3-4 weeks.

Medical action:

Methenolone is an anabolic steroid. When entering the cell nucleus, it stimulates the genetic apparatus of the cell, which leads to increased synthesis of DNA, RNA and structural proteins, activates tissue respiratory chain enzymes and stimulates tissue respiration, oxidative phosphorylation, ATP synthesis and intracellular macrodomain aggregation. It stimulates anabolic processes and inhibits the catabolic process caused by glucocorticoids.

Methenolone administration leads to increased muscle mass, reduces fat deposits, improves trophic tissues, promotes calcium deposition in bones, retains sodium and water in the body. The hematopoietic effect is determined by the increase in erythropoietin synthesis. The androgenic effect may contribute to the development of male-type secondary sexual characteristics.

Measures:

Administration should be discontinued in patients at the first signs of virilization (deepening of the voice, hirsutism, acne, clitoromegaly) to avoid irreversible changes. Systematic control of lipidemia and cholesterol levels should be performed.

Side effects:

In women – virilization symptoms, menstrual cycle disorders.

In boys: prepubertal – symptoms of virilization, arrest or arrest of growth (calcification of the epiphyseal growth zones of tubular bones); during postpubertal – gynecomastia, priapism, inhibition of spermatogenesis.

In men and women – progression of atherosclerosis, peripheral edema, impaired liver function, changes in blood count, pain in long tubular bones.